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The pathological impact of activated microglia on the BBB is suggested through the impact of inflammatory factors on endothelial TJ protein expression, which are increased in the context of microglial activation

[7] Your proactive engagement in your healthcare ensures the safest, most effective treatment outcomes

Of note, in the evoke/evoke+ trials, computerized tomography (CT) scan could be performed if magnetic resonance imaging (MRI) was contraindicated or not available, allowing for wider patient involvement

If you take your medication too often, the amount in your body could get too high, which could cause problems

[8] [9] It is important to note that this evidence relates specifically to people with type 2 diabetes and CKD